The researchers followed up with a series of biochemical and electrophysiological experiments and showed that interact with the chloride channel and the sodium channels. Gentzsch and her colleagues also confirmed in primary human airway epithelial cells from healthy subjects and patients with cystic fibrosis, that the sodium channel was in fact more active when there is no functional CFTR. Their results.
Many scientists have hypothesized that CFTR also controls the movement of other ions, such as through the epithelial sodium channel or ENaC.. Cystic fibrosis is the most common genetic disease in Caucasians, affecting approximately 1 in 3500 births in the United States. It is a defect in the gene for a protein that causes called cystic fibrosis transmembrane conductance regulator or CFTR. Well the most severe disease have very little of the CFTR protein, and this affects the way chloride ions move across many tissues in the body.Specialized testing can be gained through the Alabama Department of Public Health laboratory. For the latest information about swine flu.