In this experiment survived two of 10 animals treated with the virus ICP34.5 24 days after implantation. Of mice treated with the control virus had all 10 to day 21, a statistically significant difference death. – ‘The treatment prolonged the animals the lives of several days,’Chiocca says. ‘If we could achieve a proportional increase in humans with malignant glioma, that would be a very important step forward. ‘.
Why nestin? Normally, cells nestin only during embryonic development. After that, it is absent cells. But malignant glioma begin producing nestin again. This sets the cancer cells apart from normal cells and gave the researchers the trigger they needed.Lysosomal storage disease occur if the lysosomal, the enzymes that need to ensure their recycling lack tasks Saint abnormal accumulation the molecules the lysosome are is to to break. These disorders are responsible for the most severe cases of nerve degeneration and mental retardation in children.
Duties the protein fold causes of neurodegeneration, mental retardation.
Called Excessive accumulation in brain cells from a fat molecule GM1 ganglioside disturbs the folding of newly grouped proteins in its correct forms of, triggering nerve degeneration and mental retardation in children. This observation, from investigators at St. Jew Children Research Hospital, on the 10th September edition of of Molecular Cell publishes.